@article{oai:yamagata.repo.nii.ac.jp:00004468, author = {HATORI, Kuniyuki and IWASE, Takahiro}, journal = {山形大学紀要. 工学, Bulletin of Yamagata University. Engineering}, month = {Aug}, note = {The sliding movement of actin filaments driven by myosin motors, which underlies muscle contractions, can be observed by microscopy when purified actin and myosin are combined in vitro. At a low actin filament density, individual filaments move in random directions, whereas in condensed conditions, actin filaments gather together and are oriented in parallel. We have revealed that crowded conditions due to the presence of methylcellulose induce the alignment of bands so that actin filaments converge with collective movement (Iwase, T. et al., Biochim. Biophys. Acta 1861, pp. 2717–2725, 2017). The bands aligned at regular intervals, which seem to be determined by sliding velocity, driving force, and packing force. To understand the formation mechanism, we here present an agent-based simulation for these factors. The simulation suggests that obvious alignment of actin filaments occurs under the same magnitude of driving and packing forces, as expected in physiological conditions., 論文(Article)}, pages = {1--12}, title = {Agent-based simulation of the collective behavior of actin filaments depending on driving and packing forces}, volume = {37}, year = {2018} }