{"created":"2023-05-25T05:25:56.041800+00:00","id":4476,"links":{},"metadata":{"_buckets":{"deposit":"ae12143d-68b7-4774-ad35-8f5f5b4b66f5"},"_deposit":{"created_by":17,"id":"4476","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"4476"},"status":"published"},"_oai":{"id":"oai:yamagata.repo.nii.ac.jp:00004476","sets":["29:31:124:156"]},"author_link":["13878","13810","13879","13883","13811","13877","13814","13812","13807","13880","13808","13882","13884","13813","13809","13881"],"item_3_alternative_title_18":{"attribute_name":"その他の言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"孤発性膵神経内分泌腫瘍の外科的治療"}]},"item_3_alternative_title_19":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"コハツセイ スイシンケイ ナイブンピツシュヨウ ノ ゲカテキチリョウ"}]},"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-08-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"162","bibliographicPageStart":"139","bibliographicVolumeNumber":"36","bibliographic_titles":[{"bibliographic_title":"山形大学紀要. 医学 : 山形医学"},{"bibliographic_title":"Bulletin of the Yamagata University. Medical science : Yamagata medical journal","bibliographic_titleLang":"en"}]}]},"item_3_description_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"論文(Article)","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"　Recently, new treatment guidelines and classifications were proposed for the management of pancreatic neuroendocrine tumors（P-NETs）, and are now being used in clinical practice. The World Health Organization classification published in 2010 emphasized the importance of a grading system for P-NETs based on parameters of proliferative activity, such as mitotic count and Ki-67 labeling index, proposed by the European Neuroendocrine Tumor Society. For surgical treatment of P-NETs, it is important to select a strategy based on the degree of tumor malignancy. However, there are still no clear indications for organ-preserving pancreatic resection or lymph node dissection. This article outlines the surgical management and clinicopathological features of P-NETs. There are various surgical options, such as tumor enucleation, spleen-preserving distal pancreatectomy（SpDP），distal pancreatectomy with splenectomy, pancreatoduodenectomy, and duodenumpreserving pancreatic head resection. Hepatectomy is the first choice for liver metastasis from welldifferentiated neuroendocrine carcinoma without extrahepatic metastasis. Other treatment options are radiofrequency ablation, transarterial chemoembolization/ embolization, and liver transplantation. Systematic chemotherapy, biotherapy such as somatostatin analogue and interferon-α, and targeted therapy are used for recurrence after surgery and unresectable tumors. This article also gives details of the surgical techniques available for tumor enucleation and SpDP.","subitem_description_type":"Other"}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"13877","nameIdentifierScheme":"WEKO"}],"names":[{"name":"手塚, 康二"}]},{"nameIdentifiers":[{"nameIdentifier":"13878","nameIdentifierScheme":"WEKO"}],"names":[{"name":"木村, 理"}]},{"nameIdentifiers":[{"nameIdentifier":"13879","nameIdentifierScheme":"WEKO"}],"names":[{"name":"平井, 一郎"}]},{"nameIdentifiers":[{"nameIdentifier":"13880","nameIdentifierScheme":"WEKO"}],"names":[{"name":"菅原, 秀一郎"}]},{"nameIdentifiers":[{"nameIdentifier":"13881","nameIdentifierScheme":"WEKO"}],"names":[{"name":"渡邊, 利広"}]},{"nameIdentifiers":[{"nameIdentifier":"13882","nameIdentifierScheme":"WEKO"}],"names":[{"name":"安次富, 裕哉"}]},{"nameIdentifiers":[{"nameIdentifier":"13883","nameIdentifierScheme":"WEKO"}],"names":[{"name":"野津, 新太郎"}]},{"nameIdentifiers":[{"nameIdentifier":"13884","nameIdentifierScheme":"WEKO"}],"names":[{"name":"髙橋, 良輔"}]}]},"item_3_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15022/00004447","subitem_identifier_reg_type":"JaLC"}]},"item_3_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"山形大学"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0288-030X","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00067279","subitem_source_identifier_type":"NCID"}]},"item_3_text_33":{"attribute_name":"出版者（ヨミ）","attribute_value_mlt":[{"subitem_text_value":"ヤマガタ ダイガク"}]},"item_3_text_34":{"attribute_name":"別言語の出版者","attribute_value_mlt":[{"subitem_text_value":"Yamagata University"}]},"item_3_text_43":{"attribute_name":"資源タイプ・ローカル","attribute_value_mlt":[{"subitem_text_value":"紀要論文"}]},"item_3_text_44":{"attribute_name":"資源タイプ・NII","attribute_value_mlt":[{"subitem_text_value":"Departmental Bulletin Paper"}]},"item_3_text_45":{"attribute_name":"資源タイプ・DCMI","attribute_value_mlt":[{"subitem_text_value":"text"}]},"item_3_text_46":{"attribute_name":"資源タイプ・ローカル表示コード","attribute_value_mlt":[{"subitem_text_value":"2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tezuka, Koji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kimura, Wataru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hirai, Ichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sugawara, Shuichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe, Toshihiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ashitomi, Yuya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nozu, Shintaro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takahashi, Ryosuke"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-23"}],"displaytype":"detail","filename":"kiyoum-36-2-139to162.pdf","filesize":[{"value":"741.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"kiyoum-36-2-139to162","url":"https://yamagata.repo.nii.ac.jp/record/4476/files/kiyoum-36-2-139to162.pdf"},"version_id":"636482b4-09ea-4fbd-b591-ab9e5c319b81"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Surgical management of sporadic pancreatic neuroendocrine tumor","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Surgical management of sporadic pancreatic neuroendocrine tumor"}]},"item_type_id":"3","owner":"17","path":["156"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-08-15"},"publish_date":"2018-08-15","publish_status":"0","recid":"4476","relation_version_is_last":true,"title":["Surgical management of sporadic pancreatic neuroendocrine tumor"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-05-25T06:24:38.261478+00:00"}