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Analysis of the Metabolic Changes in pH, [HCO3-] and Pco2 in Blood Plasma at Steady State in vivo
https://yamagata.repo.nii.ac.jp/records/165
https://yamagata.repo.nii.ac.jp/records/1658857d7cd-e117-446f-b802-32df0bb9bb84
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
kiyoum-25-2-033to047.pdf (6.8 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||
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| 公開日 | 2007-10-22 | |||||||
| タイトル | ||||||||
| タイトル | Analysis of the Metabolic Changes in pH, [HCO3-] and Pco2 in Blood Plasma at Steady State in vivo | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | departmental bulletin paper | |||||||
| 著者 |
Mochizuki, Masaji
× Mochizuki, Masaji
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| 著者別名 | ||||||||
| 識別子Scheme | WEKO | |||||||
| 識別子 | 479 | |||||||
| 姓名 | 望月, 政司 | |||||||
| 内容記述 | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Previously we analysed [HCO_3^－] in blood plasma, by dividing it into a respiratory component, [HCO_3^－]^*, and a metabolic component, [HCO_3^－]^o. Assuming [HCO_3^－]^o to be independent of Pco_2, an exponential function of Pco_2 was obtained for [HCO_3^－]^*. More recently, we found, through regression analysis of the difference in pH from 7.4, that the metabolic component of pH－7.4, designated by pH－pH^*, could be evaluated by using the ratio [HCO_3^－]^o/[HCO_3^－]^*, and that this ratio, not the value for [HCO_3^－]^o, was independent of Pco_2. [HCO_3^－]^o at pH = 7.4, designated by s[HCO_3^－]^o, was calculated to test the validity of [HCO_3^－]^*, the regression functions of [HCO_3^－]^o and s[HCO_3^－]^o in venous blood, against those in arterial blood, were then calculated. Both the correlation and regression coefficients were close to unity, though the regression coefficient of [HCO_3^－]^o was slightly higher than that of s[HCO_3^－]^o. Further, in arterial and venous blood, the regression lines of pH and Pco_2 against s[HCO_3^－]^o were obtained in a number of acidotic and alkalotic patients, and the change in Pco_2, compensating for pH, was quantified. Designating [H^+] in normal blood, where s[HCO_3^－]^o = 0, by [H^+]^*, the ratio [H^+]/[H^+]^* was obtained in a number of anemic patients to check the effect of the hemoglobin concentration [Hb] on the metabolic change in pH. [H^+] agreed well with [H^+]^*, and no significant effect of [Hb] on the metabolic change in pH was found. Keywords：Acid-base imbalance, Components of [HCO_3^－], Change in pH, Metabolic change in Pco_2, Hemoglobin concentration. | |||||||
| 書誌情報 |
山形大学紀要. 医学 : 山形医学 = Bulletin of the Yamagata University. Medical science : Yamagata medical journal 巻 25, 号 2, p. 33-47, 発行日 2007-08-15 |
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| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AN00067279 | |||||||
| その他の言語のタイトル | ||||||||
| その他のタイトル | 定常空気呼吸時の血漿内pH,重炭酸イオン濃度及びCO2分圧の代謝性変化の解析 | |||||||
| タイトル（ヨミ） | ||||||||
| その他のタイトル | テイジョウ クウキ コキュウジ ノ ケッショウナイ ph ジュウタンサン イオン ノウド オヨビ CO2 ブンアツ ノ タイシャセイ ヘンカ ノ カイセキ | |||||||
| 出版者 | ||||||||
| 出版者 | 山形大学 | |||||||
| 出版者（ヨミ） | ||||||||
| 値 | ヤマガタ ダイガク | |||||||
| 別言語の出版者 | ||||||||
| 値 | Yamagata University | |||||||
| 資源タイプ | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | 論文(Article) | |||||||
| 資源タイプ・ローカル | ||||||||
| 値 | 紀要論文 | |||||||
| 資源タイプ・NII | ||||||||
| 値 | Departmental Bulletin Paper | |||||||
| 資源タイプ・DCMI | ||||||||
| 値 | text | |||||||
| 資源タイプ・ローカル表示コード | ||||||||
| 値 | 2 | |||||||
